"When I look at your heavens, the work of your fingers, the moon and the stars, which you have set in place, what is man that you are mindful of him, and the son of man that you care for him?" (Psalm 8:3-4 ESV)
"We must not belittle man's achievements. In science, for instance, man's achievements demonstrate that he is not junk, though the ends to which he often puts them show how lost he is. Our forefathers, though they believed man was lost, had no problem concerning man's significance. Man can influence history, including his own eternity and that of others. This view sees man, as man, as something wonderful.
"In contrast to this there is the rationalist who has determinedly put himself at the center of the universe and insists on beginning autonomously with only the knowledge he can gather, and has ended up finding himself quite meaningless. It comes to the same thing as Zen-Buddhism, which expresses so accurately the view of modern man: 'Man enters the water and causes no ripple.' The Bible says he causes ripples that never end. As a sinner, man cannot be selective in his significance, so he leaves behind bad as well as good marks in history; but he certainly is not a zero."
~ Francis Schaeffer, Escape From Reason, p. 268